The first ever "humanized" model for aortic valve calcification paves the way for testing potential treatments.

The Phase 2, randomized, double-blind clinical trial included 23 patients randomized to either 200 mg ataciguat (n=12) or placebo (n=11) once daily for a 12-month period. The primary Phase 2 clinical ...

Developed by Shiyou Chen and Dunpeng Cai, faculty in the School of Medicine’s Department of Surgery, the "humanized" model is currently being used to test the efficiency of various drugs and medicines ...

(UPDATED) Lipoprotein(a) is associated with the development of aortic valve calcification (AVC), but the atherogenic lipoprotein does not appear to be linked to the progression of calcification over ...

Please provide your email address to receive an email when new articles are posted on . Older patients and those with chronic kidney disease who have abdominal aortic calcification are at elevated ...

A study that combined several forms of imaging to track aortic stenosis (AS) progression in elderly patients and its relation to lipoprotein biomarkers has concluded that those biomarkers don't just ...

Aortic valve calcification--the buildup of calcium on heart valves--was once thought to be harmless but is now seen as an early sign of heart disease. In a study presented at RSNA 2011, researchers ...

In the paper, Cowell and colleagues explain that calcific aortic stenosis is an inflammatory-disease process that has many similarities with atherosclerosis. Several studies have revealed a clinical ...

A genetic component is believed to play an important role in valvular heart disease, but the specific genes involved have not been identified. Now an interntional group of researchers has identified ...

OAK BROOK, Ill. - Computed tomography (CT)-based measures of calcification in the abdominal aorta are strong predictors of heart attacks and other adverse cardiovascular events--stronger even than the ...