The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus. Inside ...

In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by ...

What can the shape of the nucleolus tell us about a cell’s response to drugs? Researchers use advanced microscopy techniques ...

Gear-obsessed editors choose every product we review. We may earn commission if you buy from a link. Why Trust Us? More than a decade of research shows that the nucleolus—the largest structure in the ...

This model of the nucleus with nucleolus (pink) shows how ribosomal DNA is correctly repaired in young cells. In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to faster ...

Researchers at Princeton University have harnessed AI to understand how drugs affect the dynamics of vital structures within ...

The nucleolus is a biomolecular condensate essential for ribosome biogenesis and cellular stress response, and it is a key target for many DNA viruses. However, little is known about how autonomous ...

Deep within the intricate world of cellular biology, scientists at Weill Cornell Medicine have made a remarkable discovery about aging that could transform our understanding of human longevity. Their ...

The eukaryotic nucleus contains many membraneless compartments or biomolecular condensates that assemble via phase-separation mechanisms, such as nucleoli, nuclear speckles, Cajal bodies and ...

Inside all living cells, loosely formed assemblies known as biomolecular condensates perform many critical functions. However, it is not well understood how proteins and other biomolecules come ...