Dupuytren contracture can appear as painless lumps or nodules under the skin of your hand, but progression over time can cause your fingers to curl in toward your palm. Dupuytren contracture is a ...

Dupuytren’s disease is a progressive fibroproliferative disorder of the palmar fascia that leads to the formation of nodules and fibrous cords, causing fixed flexion deformities of the digits and ...

Xiaflex was approved in 2010 for the treatment of Dupuytren’s contracture. Dupuytren’s contracture is a condition where nodules form under the skin in the palm of the hand. These nodules thicken and ...

Treatments for Dupuytren’s contracture include limited fasciectomy and collagenase injection. Comparisons of the effectiveness of these treatments have been limited. We performed an unblinded, ...