During the early stages of a pandemic, viruses tend to evolve in ways that enhance their ability to reproduce and spread, rather than to evade the host's immune system. The genetics and sex of the ...

Immunotherapy has changed the landscape of oncology, improving survival rates for many patients across a variety of malignancies. Two antibody-based immunotherapies, immune checkpoint inhibitors (ICI) ...

The relationship between the gut microbiome and the human body is complex. While the microbes in the human gastrointestinal tract have major impact on various aspects of health, many factors can ...

Risk of graft-vs.-host disease, an often-debilitating and sometimes-deadly bone marrow transplant complication, can be reduced by matching key immune genes in a transplant recipient and their donor.

Population genetics of host–parasite interactions examines how the genetic composition of both hosts and their parasites is shaped by co-evolutionary forces, dispersal dynamics and ecological context.

Most people who get the seasonal influenza vaccine – which contains strains of viruses from distinct virus subtypes – mount a strong immune response to one strain, leaving them vulnerable to infection ...

Plants often develop communities with microorganisms in their roots, which influences plant health and development. Although the recruitment of these microbes is dictated by several factors, it is ...

A study from Columbia University Mailman School of Public Health reports a major advance in understanding how interactions between human and viral genomes shape disease risk. The research found that ...