Medical Xpress

Scientists map how HIV hijacks human cells—and how cells can fight back

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body. Yet, even after decades ...
The Washington Post

New studies detail how HIV affects immune system, claim a drug exists to block virus

In a last-ditch effort to rid the body of HIV, droves of white bloods cells self-destruct in an explosive mass suicide that drives the progression toward AIDS, a pair of new studies has found. These ...
News Medical

Study creates genetic roadmap of how HIV virus interacts with human cells

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body. Yet, even after decades ...
Nature

Chronic inflammation degrades CD4 T cell immunity to prior vaccines in treated HIV infection

To date, our understanding of how HIV infection impacts vaccine-induced cellular immunity is limited. Here, we investigate inflammation, immune activation and antigen-specific T cell responses in ...
Nature

GITR triggering has limited impact on HIV-specific CD8 T-cell function but enhances HIV transcription reactivation from latently infected CD4 T-cells

Glucocorticoid-Induced TNFR-related protein (GITR) is a costimulatory molecule involved in the proliferation and effector functions of CD8 + and CD4 + T-cells. Recently, it has gained attention as a ...
GEN

CRISPR Screens Map Human T‑Cell Genes That Promote or Block HIV Infection

How does HIV, armed with only nine genes, manage to hijack the immune system so effectively? For decades, researchers have known that the virus depends on human proteins to enter, replicate, and ...