Meiotic crossover formation between homologous chromosomes (homologues) entails DNA double-strand break (DSB) formation, homology search using DSB ends, and synaptonemal-complex formation coupled with ...

Meiotic recombination is a major source of genetic diversity in a population. Recent advances in mapping recombination hot spots have shed light on the evolutionary dynamics of recombination hotspot ...

Researchers have identified a novel Heat Shock Factor (HSF), designated as HSF5, which plays a crucial role in the completion of meiosis and the activation of genes essential for sperm formation. This ...

Meiotic recombination assures genetic variation during breeding. During meiotic prophase I, chromosomes are organized in a loop-base array by a proteinaceous structure called meiotic chromosome axis, ...

Spo11-oligo mapping — Upper: the Spo11-oligo map agrees with ssDNA microarray analysis (Buhler et al., PLoS Biology, 2007) but is higher resolution. Lower: Agreement of the Spo11-oligo map with direct ...

The biological research of UC Santa Cruz’s Needhi Bhalla to determine the molecular motions at the heart of heredity has yielded a new discovery: The proper transfer of genetic materials depends on ...

The mystery of how meiotic arrest is maintained in mouse oocytes is revealed this week in Science by Lisa M. Mehlmann and colleagues at the University of Connecticut Health Center. The team reports ...

Chromosomes carry genetic information. Meiosis is a cell division process that produces germ cells - sperm and egg in animals, pollen and egg in plants - with half the usual chromosome number. During ...

Meiosis in human females takes place over decades. At any point in this process, an incorrect number of chromosomes can be transferred to daughter cells, resulting in aneuploid gametes, the most ...