NFL Week 4 picks, predictions: Who will win pivotal games this week?

All times MST. Click one each game for NFL Week 4 predictions and NFL Week 4 odds for that matchup.

NFL best bets for Week 4 with expert predictions, player props for Sunday

NFL Week 4 is here and we asked USA TODAY Sports' staff for their top bets for the entire NFL slate. Here are their picks and predictions.

4 bold predictions that could actually come true in NFL Week 4

Part of the lure of the NFL is that the only predictable thing about it is its unpredictability. That oblong ball does funny things sometimes, which is why almost no lead is safe, and crazy things, ...

NFL prediction panel doesn't foresee unbeaten Bills slowing down in Week 4

The Buffalo Bills look to improve their season record to 4-0 when they host the New Orleans in a rare Orchard Park meeting.

Week 4 NFL odds, lines, betting picks, spreads: 2025 predictions: Computer model backs Chargers and Bears

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since ...

NFL Week 4 predictions, picks: Our experts go head-to-head on Packers-Cowboys, Ravens-Chiefs, more

There was plenty of chaos in Week 3 of the 2025 NFL season. Sunday was the first day in league history with multiple ...