Narcolepsy, with or without cataplexy, can have a substantial detrimental effect on well-being and quality of life. Because there is no cure for this condition, current treatments aim to improve ...

Topiramate May Be Effective for Alcohol Use Disorder, PTSD Symptoms Sodium oxybate (Xyrem; Jazz), alone or in combination with modafinil, improved excessive sleepiness in patients with narcolepsy both ...

Pitolisant (Wakix) in children ages 6 years and up led to clinically meaningful improvements in narcolepsy symptoms in a phase III trial. Among 110 kids with narcolepsy with or without cataplexy, ...

A Mayo Clinic study reports that narcolepsy, a sleep disorder, is more common in men and originates in their 20s. The study, which appeared in a recent edition of the journal Sleep, also found that ...

INDIANAPOLIS -- Extended-release sodium oxybate (Lumryz) taken once before bedtime was preferred by patients with narcolepsy over twice-nightly dosing and was generally well tolerated, according to ...

Oct. 25, 2002 — Low cerebrospinal fluid (CSF) levels of hypocretin are diagnostic for narcolepsy, according to a report in the October issue of Archives of Neurology. Because hypocretin neurons are ...

For years, Julie Flygare kept her condition private. She hadn’t liked people’s reactions on the occasions when she had opened up and shared her story. People thought it was a joke or not important. In ...

Pitolisant is now the only treatment option not scheduled as a controlled substance that is indicated for both excessive daytime sleepiness and cataplexy in pediatric and adult patients. The Food and ...

WESTCHESTER, Ill. -- Persons with narcolepsy with cataplexy have low levels of cerebrospinal fluid (CSF) hypocretin-1, a protein thought to help regulate sleep and wakefulness, according to a study ...

The FDA has approved a supplemental new drug application for pitolisant (Wakix, Harmony Biosciences) for the treatment of cataplexy in children as young as 6 years with narcolepsy. Pitolisant was ...