Podocytes are key components of the glomerular filtration barrier — a specialized structure that is responsible for the filtration of blood by the kidneys. They therefore exist in a unique ...

The kidneys are vital organs that sustain life by filtering the blood and producing urine. This filtration process takes place in specialized structures called glomeruli, where podocytes play a ...

A single podocyte was reconstructed in three dimensions based on serial glomerular section images obtained by array tomography. The three-dimensional reconstruction enabled quantitative volume ...

A new research paper titled "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span" has been published in Aging. The decrease in the podocytes' lifespan and health span ...

Unlike other human stem cells, Induced pluripotent stem cells (iPS cells) can be produced directly from adult cells. Now, researchers have shown that human kidney podocytes produced from iPS cells via ...

Acute kidney injury (AKI), frequently caused by ischemia 1,2, is a common clinical condition associated with high morbidity and mortality 3,4. Although excessive proteins in urine or proteinuria -due ...

BIDMC Research Briefs showcase groundbreaking scientific advances that are transforming medical care. Special cells called podocytes aid the kidneys as they clean the blood and balance the body's ...

Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the ...

A newly-established protocol offers hope for kidney disease modeling, drug discovery, and potential cell therapies. Previous work from the Wyss Institute at Harvard University established a protocol ...

Scientists overturn conventional wisdom about kidney disease. BIDMC Research Briefs showcase groundbreaking scientific advances that are transforming medical care. Special cells called podocytes aid ...

BIDMC Research Briefs showcase groundbreaking scientific advances that are transforming medical care. Special cells called podocytes aid the kidneys as they clean the blood and balance the body's ...