Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres — regions of repetitive DNA sequences and a protein structure — protect the tips of chromosomes from damage. Every ...

Please provide your email address to receive an email when new articles are posted on . Researchers developed a multi-ancestry polygenic score using data from two genome-wide association studies.

A new study links telomere length and polygenic risk scores to IPF development, highlighting genetic drivers beyond rare variants. The role of polygenic risk scores in patients with idiopathic ...

The results of research by scientists at University College London (UCL), Imperial College London, and the MRC Laboratory of Medical Sciences, indicate that a potentially life-changing heart condition ...

New genetic research shows a simple genetic test can predict who’s most at risk for obesity, offering hope for early prevention, but also raises tough questions about genetic fairness and healthcare ...

The optimism is not unfounded. In specific, well-defined clinical scenarios, polygenic scores are beginning to demonstrate some tangible utility. For cardiovascular disease, MI-GENES, a 10-year follow ...

Polygenic risk scores (PRSs) are a cutting-edge tool in genetics, combining information from genetic markers across the genome to estimate a person's risk of developing certain diseases, such as ...

Polygenic risk scores for IOP and VCDR significantly enhance glaucoma risk prediction, especially for primary open-angle glaucoma. The study utilized data from multiple cohorts, including the Canadian ...

Cost-utility studies provide critical information for the costs and benefits of using any new test, typically building on existing public health and screening programmes, within a defined population.

Daphne O. Martschenko and Sam Trejo both want to make the world a better, fairer, more equitable place. But they disagree on whether studying social genomics—elucidating any potential genetic ...