Adolescence is widely thought to be a time when the brain trims away excess neural connections, refining circuits through synaptic pruning. New research now suggests this view may be incomplete.

Research led by SUNY Downstate Medical Center has identified a brain receptor that appears to initiate adolescent synaptic pruning, a process believed necessary for learning, but one that appears to ...

Researchers from Kyushu University discovered a previously unrecognized synaptic "hotspot" that forms during adolescence, challenging the long-held view that adolescent brain development was dominated ...

Synaptic pruning is a little like sleep. We know both processes are important to healthy brain function, but we don't know exactly how they happen, nor how to reliably treat problems in the system.

Every thought, memory, and feeling we experience depends on trillions of tiny connection points in the brain called synapses. These are the junctions where one neuron passes signals to another, ...

The hippocampus follows a "tabula plena" model, starting with dense, random connections that are pruned into an efficient ...

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These findings support Anavex’s intent to advance blarcamesine into pivotal clinical studies to further evaluate its potential in addressing unexpectedly common CNS disease mechanisms NEW YORK, April ...