Two-component regulatory systems constitute a widespread mechanism by which bacteria detect and adapt to antimicrobial threats. Each system comprises a membrane-associated sensor histidine kinase that ...

In this study, we comprehensively investigated the DbfRS regulatory network, defining its sensory inputs, physiological outputs, and fitness consequences. We identified a previously uncharacterized ...

A team has uncovered how a common bacterial pathogen uses a single protein to quietly undermine the human immune system, by both shutting down key warning signals and blocking the cell’s ability to ...