Massive Russian strikes on Ukraine’s second-largest city killed at least five people on Saturday, officials said, one night after Moscow carried out one of the war’s largest aerial assaults on Ukraine.

Ukraine says that a large Russian drone-and-missile attack has targeted the eastern city of Kharkiv, killing at least three people and injuring 21.

Photos showed burnt and partially destroyed houses and vehicles, and rescuers carrying the injured to safety and removing debris.