Tau tangles may abound in neurons, but they could leave an epigenetic imprint on a different cell—oligodendrocytes. So say scientists led by Nilüfer Ertekin-Taner at the Mayo Clinic in Jacksonville, ...
As the brain’s jumpy immune responders, microglia have the potential to ward off AD pathogenesis … or make it worse. On which side of this fine line they fall seems to change as disease progresses, ...
Comments Meet Tanycytes: Bridging Brain and Body, These Cells May Dispose of Tau 13 Mar 2026 ...
Contact Information Kellen Petersen, Ph.D. St. Louis, United States Professional Information InstructorWashington University in St. Louis https://kellenpetersen ...
Blood tests for Alzheimer’s disease are rapidly transforming the way clinicians diagnose the disease. Still, some scientists urge caution when interpreting results, arguing that the meaning of a ...
Rarely do scientists discover a new pathogenic mutation for a sporadic disease. Even less often do they find one that explains half the cases. Pinning disease on a dinucleotide expansion? That’s a new ...
Scientists continue to look for new ways to target sticky amyloid plaques in the brain. The approved immunotherapies have well-known limitations. In the March 5 Science, Marco Colonna and colleagues ...
Tau made in the brain eventually shows up in blood, but scientists still aren’t sure how it gets there. Now, research featured in Cell Press Blue offers a new idea. This journal launched in January to ...
Circular RNAs are the byproducts of aberrant “backsplicing.” They accumulate and cause problems in the brain with age. According to a study published March 5 in Molecular Cell, ribonuclease κ—an ...
The MCI-Park mice are compound mutant (Ndufs2fl/fl; DAT IREScre/+) animals in which Ndufs2, a gene encoding a core subunit of the mitochondrial respiratory chain, is selectively inactivated in ...
An interactive timeline of the evolution of Alzheimer's Disease research.
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