Two Types. Confocal microscopy reveals α-synuclein (green) and lipids (red) in three adjacent inclusions (left and right). The white arrows point to Type I inclusions loaded with lipids. Blue ...

Immunotherapy can remove extracellular amyloid plaques from Alzheimer’s brain, but has so far failed to clear intracellular tau tangles. Now, two papers propose a solution: tagging them for ...

Alzheimer’s is a multifaceted disease, particularly in its sporadic, late-onset form. Myriad factors—genetics, environment, ...

But some 80 percent of people with Parkinson's disease have GI problems, such as acid reflux, irritable bowel syndrome, and constipation, which often emerge decades before motor difficulties do. This ...

In Alzheimer’s disease, tau tangles accumulate in the temporal lobe and cortex, but spare other regions such as the cerebellum and brainstem. In a July 31 preprint on bioRxiv, scientists led by Huda ...

On Tuesday September 10, Francisco Lopera died of cancer at his home in Medellin, Colombia. He was 73, and only just beginning to see his life’s work come to fruition.

Could one tiny little amino acid derivative make Alzheimer’s disease a whole lot worse? In the August 25 Science, researchers led by Katrin Andreasson, Stanford University School of Medicine, report ...

Decades before memory loss becomes a concern, the biological processes that lead to Alzheimer’s disease are underway in the brain. Could proteins in the blood sound the alarm for this pending crisis?

I am a co-founder of Treventis Corp. which is a startup biotech dedicated to the design and development of novel small molecule inhibitors of beta-amyloid and tau misfolding and oligomerization.

Oct.1997 - Sep. 2000, Ph.D. in Bioorganic Chemistry, Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University, Sapporo, Japan Sep.1990 ...