After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The ...

Although the Arabidopsis thaliana RPD3-type histone deacetylase HDA19 and its close homolog HDA6 participate in SIN3-type histone deacetylase complexes, they display distinct biological roles, with ...

imageimageTransposable elements contribute to evolution, but their own diversification remains incompletely understood. Here, insect endogenous retroviruses (iERVs) are shown to diversify through the ...

Stabilization of microtubule plus end-directed kinesin CENP-E at the metaphase kinetochores is important for chromosome alignment, but its mechanism remains unclear. Here, we show that CKAP5, a ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

The ER membrane protein SELENOT has been previously suggested to be neuroprotective, but its contribution to neuronal pathophysiology has not been thoroughly investigated. This study reports that ...

Aggressive prostate cancer (PCa) variants associated with androgen receptor signaling inhibitor (ARSI) resistance and metastasis remain poorly understood. Here, we identify the axon guidance ...

imageimagePatients with inflammatory arthritis face increased heart and lung complications, which current treatments fail to address. This study identifies a novel therapeutic approach by selective ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

imageimageLRBA regulates autophagy and antigen presentation, shedding light on the mechanism of immune dysregulation in LRBA deficiency. LRBA directly interacts with PIK3R4 and FYCO1, promoting ...

Ductular reaction (DR) is the hallmark of cholestatic diseases manifested in the proliferation of bile ductules lined by biliary epithelial cells (BECs). It is commonly associated with an increased ...

Fungal infections and autoimmunity share a complex, bidirectional relationship that significantly impacts patient outcomes. Emerging evidence highlights how fungal pathogens contribute to autoimmune ...