Chromosome ends require protection from the DNA repair machinery. This work demonstrates that TelN protein, the telomere ...

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The EMBO Journal has been EMBO's flagship publication for 40 years. With a scope that spans all areas of molecular biology, the journal has an international reputation for quality and originality. The ...

In this issue of The EMBO Journal, Chandler et al, demonstrate in a neonatal mouse model that maternal antibodies interfere ...

Conjugation is mediated by a large molecular machinery termed Type IV secretion system (T4SS), embedded within the donor cell ...

Most proteins in blood are measured outside their functional and cellular context. Machine learning was used to integrate ...

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An epigenome-wide study uncovers ancestry-associated DNA methylation reprogramming in African prostate tumours, implicating enhancer dysregulation and developmental pathway activation in aggressive ...

Raw sequencing data are processed and aligned to give count matrices, which represent the start of the workflow. The count data undergo pre‐processing and downstream analysis. Subplots are generated ...

Understanding temporal dynamics in tissue biology is key to linking transcriptomic snapshots to physiological function.

Several recent studies show that the E3 ligase RNF114 recognises a hybrid ADP-ribose-ubiquitin modification on substrate ...

Basic research, often termed fundamental, frontier, blue-sky, curiosity-driven—or even useless—is the pursuit of knowledge ...