PH proportional hazards, HR hazard ratio, CI confidence interval. a Per 10-unit increase. b Per 1-cm increase. c pT3 vs. pT1-2 (reference). d III-IV vs. I–II (reference). e Per 10-year increase. Bold ...
Transient receptor potential vanilloid 1 (TRPV1) is a capsaicin-sensitive ion channel implicated in pain sensation. While TRPV1 potentiation in hyperalgesia development has been extensively ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. T cell receptors (TCR) and gene expression ...
This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. miR153 regulates inhibitory synapses by ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. CD8 + T cells have critical roles in tumor ...
A jackal hunting mice at Etosha National Park, Namibia. The photographer, Hanna Kraus, is a PhD student at the Department of Molecular Evolution and Development of the University of Vienna. Her ...
Thus, Skn7p plays a part in numerous biological stress responses. In this paper we further elucidate a role for Skn7p in stress‐activated signal transduction. We present biochemical and genetic ...
A non-canonical role of the inner kinetochore in regulating sister-chromatid cohesion at centromeres
The inner kinetochore is well-known for connecting centromeric chromatin to the microtubule-binding outer kinetochore. This work reveals a non-canonical role for the inner kinetochore in binding ...
Binding of TGFβ/BMP factors to their receptors leads to translocation of Smad proteins to the nucleus where they activate transcription of target genes. The two‐handed zinc finger proteins encoded by ...
Hepatitis C virus proteins are synthesized as a polyprotein cleaved by a signal peptidase and viral proteases. The behaviour of internal signal sequences at the C‐terminus of the transmembrane domains ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Kareniacean plastids are distinct from those ...
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