When your team wins, it is a shot in the arm to your self-esteem. When it loses there is a loss of self-esteem. And we carry ...

The Chicago White Sox staged a two-out rally in the 9th but fell to the San Diego Padres 3-2 in 10 on Friday. The Sox are ...

Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

The San Diego Padres (88-66) take on the Chicago White Sox (36-118), who will be trying to halt a three-game losing streak, ...

Lenyn Sosa hit a tying two-run homer with two outs in the ninth inning, but the Chicago White Sox lost their 118th game when ...

Fernando Tatis Jr.'s run-scoring hit leading off the 10th lifted the Padres to a 3-2 victory over the White Sox Friday.

As the defeats continue to mount, the White Sox have joined the discussion of the most infamous baseball teams of all time.

Eric Wagaman scored with one out in the 13th inning when Jordyn Adams' grounder deflected off the glove of third baseman ...

The Chicago White Sox trailed by two runs as Sosa batted with a runner on and two outs in the ninth inning against the San Diego Padres at Petco Park. After a ball, Sosa fouled off the next three ...

White sox ninth. Andrew Benintendi strikes out swinging. Andrew Vaughn grounds out to shortstop, Xander Bogaerts to Donovan Solano. Gavin Sheets walks. Lenyn Sosa homers to center field. Gavin Sheets ...

BOTTOM LINE: The Chicago White Sox, on a three-game losing streak, take on the San Diego Padres. San Diego is 43-36 in home games and 88-66 overall. The Padres have a 37-20 record in games when they ...

Analyzing Friday’s Chicago White Sox at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.