The Arizona Cardinals will host the Detroit Lions at State Farm Stadium Sunday afternoon in Week 3. The Cardinals have not beaten the Lions since 2015, going 0-4-1 against them since then and haven't beaten their starting quarterback,

The Detroit Lions need to contain Kyler Murray and get their rushing attack going to avoid falling below .500 for the first time since late in 2022.

The Detroit Lions and Arizona Cardinals get together for the first time since 2021 in a late-afternoon kickoff in Week 3. Both teams are 1-1 entering the matchup, with each team recording their victory over the Los Angeles Rams.