The Indianapolis Colts are on the road to take on the Kansas City Chiefs in week 12 of the 2025 season, kickoff is at 1:00 p.m. EST. Fresh off of their bye the Colts travel to take on the 5-5 Chiefs.

You've seen the model's best bets for Indianapolis Colts vs. Kansas City Chiefs. Now, get against the spread, total and money-line picks for every Week 12 NFL game here, all from the model that's simulated every game 10,000 times.

The Kansas City Chiefs' offense has raised some alarming questions that it needs to answer against the Indianapolis Colts in Week 12.

It would be difficult to find a more surprising NFL team this season than the Indianapolis Colts. Part of their success has been the revival of quarterback Daniel Jones’ career, but a lot of it also has to do with their stacked defense,

The Kansas City Chiefs and star QB Patrick Mahomes got some major injury news just hours before their matchup vs. the Colts.