The 49ers welcome the Panthers for a Week 12 prime-time clash between two teams working to secure a playoff spot.

Who is playing on Monday Night Football? Check out complete MNF game schedule, including Panthers vs 49ers matchup for NFL ...

USA Today's NFL experts make their picks for a Week 12 showdown between the San Francisco 49ers and Carolina Panthers ...

At least one analyst expects McMillan to go off against the 49ers. Andrew Buller-Russ at Sportsnaut is predicting that ...

The Panthers will make their return engagement to MNF at San Francisco, and have a chance to remain in the NFC South playoff ...

The San Francisco 49ers are back in playoff contention with Brock Purdy returning as their starting quarterback.

DFS Millionaire Mike McClure reveals his top daily Fantasy picks for Raiders vs. Cowboys on 'Monday Night Football' ...

CBS Sports NFL expert Will Brinson breaks down his top Monday Night Football plays for Week 11 of the NFL season ...

Rohit Ponnaiya breaks down his early Panthers vs. 49ers predictions ahead of Monday Night Football in Week 12. Free NFL picks ...

Fans can listen to Monday Night Football live with SiriusXM on channel 88, NFL Radio, for the national broadcast.

Carolina is coming off a huge emotional win over Atlanta, but a much tougher opponent is lurking next on the schedule.

Week 11 of the NFL season will come to a conclusion tonight when the Dallas Cowboys and Las Vegas Raiders go head to head in ...